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货号： bs-3865R 基本售价： 780.0 元 规格： 50ul
- 规格：50ul
- 价格：780.00元
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-3865R
- 英文名称
- PRDX5+PRDX6
- 中文名称
- 过氧化还原酶5/6抗体
- 别 名
- 1 Cys; 1 Cys peroxiredoxin; 1 Cys PRX; 1 cysPrx; 24 kDa protein; Acidic calcium independent phospholipase A2; aiPLA2; Antioxidant protein 2; AOP2; Aop2 rs3; Brp 12; Ciliary body glutathione peroxidase; CP 3; GPx; Liver 2D page spot 40; Ltw4; Lvtw 4; Non selenium glutathione peroxidase; NSGPx; ORF06; p29; Peroxiredoxin6; Peroxiredoxin 6; Peroxiredoxin-6; Peroxiredoxin5; Peroxiredoxin 5; Peroxiredoxin-5; PHGPx; Phospholipase A2 lysosomal; PLA2; PRDX 6; Prdx5; PRDX6; PRX; Red blood cells page spot 12; Thiol specific antioxidant protein; AA690119; Prdx6 rs3.
- 规格价格
- 50ul/780元购买 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 50ul 100ul 200ul
- 研究领域
- 肿瘤 细胞生物 免疫学 细胞凋亡 干扰素
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 18/25kDa
- 细胞定位
- 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Peroxiredoxin 6:51-150/214
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Peroxiredoxin (Prx) is in the peroxidase family, whose mammalian members have been known to contribute to cell proliferation, differentiation and apoptosis. Many isoforms (about 50 proteins), collected in accordance with amino acid sequence homology, particularly the amino terminal region containing active site cysteine residue, and the thiol specific antioxidant activity, distribute throughout all the kingdoms. Mammalian Prx consists of 6 different members grouped into typical 2 Cys, atypical 2 Cys Prx, and 1 Cys Prx. Except PrxVI belonging to the 1 Cys Prx subgroup, the other five 2 Cys Prx isotypes have the thioredoxin dependent peroxidase(TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20–30 kDa in molecular size and vary in subcellularlocalization: PrxI, II, and VI in cytosol; PrxIII in mitochondria; PrxIV in ER and secretion; PrxV shows complicated distribution including peroxisome, mitochondria and cytosol.
Subunit:
Monomer.
Subcellular Location:
Mitochondrion. Cytoplasm. Peroxisome.
Tissue Specificity:
Widely expressed.
Similarity:
Belongs to the peroxiredoxin 2 family.
Contains 1 thioredoxin domain.
SWISS:
P30044
Gene ID:
25824
Database links:Entrez Gene: 25824 Human
Entrez Gene: 54683 Mouse
Entrez Gene: 113898 Rat
Omim: 606583 Human
SwissProt: P30044 Human
SwissProt: P99029 Mouse
SwissProt: Q9R063 Rat
Unigene: 502823 Human
Unigene: 279782 Mouse
Unigene: 2944 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
- 产品图片
Tissue/cell: mouse brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-PRDX5+PRDX6 Polyclonal Antibody, Unconjugated(bs-3865R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
Tissue/cell: human lung cancer tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-PRDX5 + PRDX6 Polyclonal Antibody, Unconjugated(bs-3865R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining