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货号： bs-11396R-PE-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11396R-PE-Cy5.5
- 英文名称
- Anti-rSec6/PE-Cy5.5
- 中文名称
- PE-Cy5.5标记的胞吐分泌蛋白Sec6抗体
- 别 名
- EXOC 3; EXOC3; Exocyst complex component 3; Exocyst complex component Sec 6; Exocyst complex component Sec6; rSec 6; Sec 6; Sec-6; Sec 6 homolog; Sec 6p; Sec6; SEC6 L1; SEC6 like 1; Sec6 protein; SEC6L1; Sec6p; EXOC3_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 细胞类型标志物
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 87kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human rSec6 (714-756aa)
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
Function:
Sec6 is a component of the exocyst complex involved in the docking of exocystic vesicles with fusions site on the plasma membrane.
Subunit:
The exocyst complex is composed of EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7 and EXOC8. Interacts with EXOC3L1 (By similarity). Interacts with BIRC6/bruce. Interacts with MYRIP
Subcellular Location:
Cytoplasmic
Similarity:
Belongs to the SEC6 family.
Database links:Entrez Gene: 11336 Human
Entrez Gene: 211446 Mouse
Entrez Gene: 252881 Rat
Omim: 608186 Human
SwissProt: O60645 Human
SwissProt: Q6KAR6 Mouse
SwissProt: Q62825 Rat
Unigene: 481464 Human
Unigene: 489612 Mouse
Unigene: 6753 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.