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货号： bs-8750R-PE-Cy5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-8750R-PE-Cy5
- 英文名称
- Anti-ARF4/PE-Cy5
- 中文名称
- PE-Cy5标记的ADP核糖基化因子4抗体
- 别 名
- ADP ribosylation factor 2;ADP ribosylation factor 4;ADP-ribosylation factor 4;ARF2;ARF4;ARF4_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 结合蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 20kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ARF4
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene is a member of the human ARF gene family whose members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 5 ARF proteins and 11 ARF-like proteins and constitute one family of the RAS superfamily. The ARF proteins are categorized as class I, class II and class III; this gene is a class II member. The members of each class share a common gene organization. The ARF4 gene spans approximately 12kb and contains six exons and five introns. This gene is the most divergent member of the human ARFs. Conflicting map positions at 3p14 or 3p21 have been reported for this gene. [provided by RefSeq, Jul 2008]
Function:
GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
Subcellular Location:
Golgi apparatus.
Similarity:
Belongs to the small GTPase superfamily. Arf family.
Database links:Entrez Gene: 769725Chicken
Entrez Gene: 518601Cow
Entrez Gene: 378Human
Entrez Gene: 11843Mouse
Entrez Gene: 595108Pig
Entrez Gene: 79120Rat
Omim: 601177Human
SwissProt: Q3SZF2Cow
SwissProt: P18085Human
SwissProt: P61750Mouse
SwissProt: P61751Rat
Unigene: 652183Human
Unigene: 297768Mouse
Unigene: 35935Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.