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货号： bs-19543R-PE-Cy5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19543R-PE-Cy5
- 英文名称
- Anti-NUP155/PE-Cy5
- 中文名称
- PE-Cy5标记的核孔复合蛋白Nup155抗体
- 别 名
- 155 kDa nucleoporin; D930027M19Rik; KIAA0791; mKIAA0791; N155; NU155_HUMAN; Nuclear pore complex protein Nup155; nucleoporin 155kD; Nucleoporin Nup155; Nup155.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 染色质和核信号 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Zebrafish,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 155kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NUP155
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Nucleoporins are proteins that play an important role in the assembly and functioning of the nuclear pore complex (NPC) which regulates the movement of macromolecules across the nuclear envelope (NE). The protein encoded by this gene plays a role in the fusion of NE vesicles and formation of the double membrane NE. The protein may also be involved in cardiac physiology and may be associated with the pathogenesis of atrial fibrillation. Alternative splicing results in multiple transcript variants of this gene. A pseudogene associated with this gene is located on chromosome 6. [provided by RefSeq, May 2013]
Function:
Essential component of nuclear pore complex. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport.
Subcellular Location:
Nucleus > nuclear pore complex. Nucleus membrane. Nucleus membrane. In mitosis, assumes a diffuse cytoplasmic distribution probably as a monomer, before reversing back into a punctate nuclear surface localization at the end of mitosis.
Tissue Specificity:
Expressed in all tissues tested, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Post-translational modifications:
Phosphorylated. Phosphorylation and dephosphorylation may be important for the function of NUP155 and may play a role in the reversible disassembly of the nuclear pore complex during mitosis.
Similarity:
Belongs to the non-repetitive/WGA-negative nucleoporin family.
Database links:Entrez Gene: 9631Human
Entrez Gene: 427443Chicken
Entrez Gene: 461913Chimpanzee
Entrez Gene: 506738Cow
Entrez Gene: 479360Dog
Entrez Gene: 101133763Gorilla
Entrez Gene: 100053405Horse
Entrez Gene: 170762Mouse
Entrez Gene: 100437988Orangutan
Entrez Gene: 100517061Pig
Entrez Gene: 100347238Rabbit
Entrez Gene: 117021Rat
Entrez Gene: 706019 Rhesus monkey
Entrez Gene: 380494 Xenopus laevis
Entrez Gene: 100379911 Xenopus tropicalis
Omim: 606694Human
SwissProt: O75694Human
SwissProt: Q99P88Mouse
SwissProt: P37199Rat
Unigene: 547696Human
Unigene: 295168Mouse
Unigene: 11328Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.