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货号： bs-19467R-PE-Cy5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19467R-PE-Cy5
- 英文名称
- Anti-PSMD13/PE-Cy5
- 中文名称
- PE-Cy5标记的26S蛋白酶体非ATP酶调节亚基13抗体
- 别 名
- 26S proteasome non ATPase regulatory subunit 13; 26S proteasome non-ATPase regulatory subunit 13; 26S proteasome regulatory subunit p40.5; 26S proteasome regulatory subunit RPN9; 26S proteasome regulatory subunit S11; 26S proteasome subunit p40.5; HSPC027; P40.5; Proteasome (prosome, macropain) 26S subunit, non ATPase, 13; PSD13_HUMAN; psmD13; Rpn9; S11.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 泛素
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Cow,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 43kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PSMD13
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Function:
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Subunit:
Component of the PA700 complex.
Similarity:
Belongs to the proteasome subunit S11 family.
Contains 1 PCI domain.
Database links:Entrez Gene: 5719Human
Entrez Gene: 450913Chimpanzee
Entrez Gene: 513525Cow
Entrez Gene: 447560 Xenopus laevis
Entrez Gene: 447992 Xenopus tropicalis
Omim: 603481Human
SwissProt: Q5E964Cow
SwissProt: Q9UNM6Human
Unigene: 134688Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.