9,11-methane-epoxy Prostaglandin F1α
货号：
10007850-1mg 基本售价：
4032.0 元 规格：
1 mg
产品信息
概述| 货号 | 10007850-1mg |
| 描述 | Prostaglandin (PG) endoperoxides are intermediates in the biosynthesis of PGs, thromboxanes, and prostacyclin. The endoperoxides, PGH2 and PGG2, induce rapid and irreversible aggregation of human platelets.1PGH1 and PGG1 are known to contract smooth muscle preparations, but are lacking in aggregatory effects. 9,11-methane-epoxy Prostaglandin F1α (9,11-methane-epoxy PGF1α) is a stable epoxymethano analog of PGH1 that produces a strong and dose-related aggregation of washed rabbit platelets (EC50 = 0.88 µM) and contraction of rabbit aortic strips (EC50 = 0.11 µM).1 9,11-methane-epoxy PGF1α induces contraction of guinea pig tracheas (EC50 = 3.4 µM) with a maximal contraction of about 60% of that caused by a submaximal dose of histamine. |
| 别名 | 9,11-Epoxymethano PGH1; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Morita, A.,Nishino, H.,Hasegawa, K., et al. Biological activities of prostaglandin H1 analogs. Prostaglandins 18(4), 529-540 (1979).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥96% |
| 计算分子量 | 352.5 |
| 分子式 | C21H36O4 |
| CAS号 | 72517-81-8 |
| 稳定性 | ≥ 1 year |
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