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货号： bs-7826R-PE-Cy5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-7826R-PE-Cy5
- 英文名称
- Anti-RABGAP1/PE-Cy5
- 中文名称
- PE-Cy5标记的Rab蛋白GTP酶激活蛋白1抗体
- 别 名
- Rab GTPase-activating protein 1; Rab GAP1, GAP and centrosome associated protein; HSPC094; Rab GTPase activating protein 1; Rab6 GTPase activating protein GAPCenA; RBGP1_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 细胞周期蛋白 细胞类型标志物 G蛋白信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 122kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human RABGAP1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Rab GTPase-activating protein 1 is a 1,069 amino acid cytoplasmic protein containing one PID domain and one Rab-GAP TBC domain. Rab GAP1 acts as a GTPase-activating protein of Rab 6A in the Rab 6A-mediated pathway, which is involved in the metaphase-anaphase transition. Expressed as four alternatively spliced variants, Rab GAP1 may also be involved in the microtubule nucleation by centrosome and in Golgi dynamics during the cell cycle. Rab GAP1 is encoded by a gene located on human chromosome 9, which consists of about 145 million bases, 4% of the human genome and encodes nearly 900 genes.
Function:
May act as a GTPase-activating protein of RAB6A. Mayplay a role in microtubule nucleation by centrosome. Mayparticipate in a RAB6A-mediated pathway involved in themetaphase-anaphase transition.
Subunit:
Interacts with RAB6A and tubulin gamma.
Subcellular Location:
Cytoplasm, cytosol. Cytoplasm, cytoskeleton,centrosome. Note=Predominantly cytosolic but also associated withthe centrosome.
Similarity:
Contains 1 PID domain.
Contains 1 Rab-GAP TBC domain.
Database links:Entrez Gene: 519260 Cow
Entrez Gene: 23637 Human
Entrez Gene: 227800 Mouse
Entrez Gene: 311911 Rat
SwissProt: Q9Y3P9 Human
SwissProt: A2AWA9 Mouse
Unigene: 271341 Human
Unigene: 383192 Mouse
Unigene: 14944 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.