产品中心
当前位置：首页>产品中心Anti-IL22R
货号： bs-2624R 基本售价： 780.0 元 规格： 50ul
- 规格：50ul
- 价格：780.00元
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-2624R
- 英文名称
- IL22R
- 中文名称
- 白介素22受体抗体
- 别 名
- IL-22R; CRF2 9; IL22 Receptor Alpha; cytokine receptor classII member 9; cytokine receptor family 2 member 9; IL-22 receptor subunit alpha-1; IL-22R-alpha-1; IL22R; IL22R1; IL22RA1; ILTIF R1 chain; Interleukin 22 Receptor alpha 1; Interleukin 22 Receptor; Interleukin-22 receptor subunit alpha-1; ZcytoR11; I22R1_HUMAN; IL-22 receptor subunit alpha-1; IL-22RA1; Cytokine receptor class-II member 9; Cytokine receptor family 2 member 9; CRF2-9.
- Specific References (2) | bs-2624R has been referenced in 2 publications.[IF=2.09] Guo, Yujie, et al. "IL-22-producing Th22 cells play a protective role in CVB3-induced chronic myocarditis and dilated cardiomyopathy by inhibiting myocardial fibrosis." Virology Journal 11.1 (2014): 2511. IHC-P ; Mouse.PubMed:25547181[IF=0.00] Zhang, Yan, and Mikhail G. Kolonin. "Cytokine signaling regulating adipose stromal cell trafficking." Adipocyte 5.4 (2016): 369-374. IHC-P ; Mouse.PubMed:27994950
- 规格价格
- 50ul/780元购买 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 50ul 100ul 200ul
- 研究领域
- 细胞生物 免疫学 信号转导 细胞膜受体
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 61kDa
- 细胞定位
- 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human IL-22R:41-150/574 <Extracellular>
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36. [provided by RefSeq, Jul 2008].
Function:
Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.
Subunit:
Heterodimer with IL10RB and with IL20RB.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Expressed in kidney, liver and lung.
Similarity:
Belongs to the type II cytokine receptor family.
Contains 2 fibronectin type-III domains.
SWISS:
Q8N6P7
Gene ID:
58985
Database links:Entrez Gene: 58985 Human
Omim: 605457 Human
SwissProt: Q8N6P7 Human
Unigene: 110915 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
- 产品图片
Sample:
Lane1: Liver(Mouse) Lysate at 30 ug
Lane2: Intestinal(Mouse) Lysate at 30 ug
Primary: Anti-IL22R (bs-2624R) at 1:300 dilution;
Secondary: HRP conjugated Goat-Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000 dilution;
Predicted band size : 61kD
Observed band size : 61kD
Sample:
placenta (Mouse) Lysate at 40 ug
Primary: Anti-IL22R (Bs-2624R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 61 kD
Observed band size: 65 kD