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货号： bs-23420R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-23420R-PE-Cy3
- 英文名称
- Anti-Adenylate kinase isoenzyme 6/PE-Cy3
- 中文名称
- PE-Cy3标记的腺苷酸激酶同工酶6抗体
- 别 名
- AK6; Coilin Interacting Nuclear ATPase Protein; Adrenal Gland Protein AD-004; EC 2.7.4.3; HCINAP; CINAP; Coilin-Interacting Nuclear ATPase Protein; Dual Activity Adenylate Kinase/ATPase; ATP-AMP Transphosphorylase 6; Adenylate Kinase Isoenzyme 6; Coilin Interacting Protein; AK/ATPase; CGI-137; AD-004; CIP; KAD6_HUMAN;
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 发育生物学 激酶和磷酸酶
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 20kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Adenylate kinase isoenzyme 6
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.05M PB, pH 7.5.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a protein that belongs to the adenylate kinase family of enzymes. The protein has a nuclear localization and contains Walker A (P-loop) and Walker B motifs and a metal-coordinating residue. The protein may be involved in regulation of Cajal body formation. In human, AK6 and TAF9 (GeneID: 6880) are two distinct genes that share 5 exons. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Function:
Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. AMP and dAMP are the preferred substrates, but CMP and dCMP are also good substrates. IMP is phosphorylated to a much lesser extent. All nucleoside triphosphates ATP, GTP, UTP, CTP, dATP, dCTP, dGTP, and TTP are accepted as phosphate donors. CTP is the best phosphate donor, followed by UTP, ATP, GTP and dCTP. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.
Subunit:
Monomer and homodimer (By similarity). Interacts with COIL (via C-terminus).
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, chorionic villi and the central nervous system.
Similarity:
Belongs to the adenylate kinase family. AK6 subfamily.
Database links:Entrez Gene: 102157402 Human
Entrez Gene: 6880 Human
Entrez Gene: 102216272 Mouse
Entrez Gene: 102238592 Rat
SwissProt: Q9Y3D8 Human
SwissProt: Q8VCP8 Mouse
SwissProt: Q9TTU2 Rabbit
SwissProt: Q5EB68 Rat
Unigene: 653163 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.