TLR9 Explorer
货号:
130-100-589 基本售价:
询价 规格:
EA
产品信息
概述货号 | 130-100-589 |
描述 | Oligodeoxyribonucleotides containing CpG motifs (CpG ODNs) are widely used for activation of immune cells, such as human PBMCs, murine splenocytes or isolated immune cells, e.g., B cells and pDCs. They also activate signalling in TLR9-expressing recombinant cell lines.This kit consists of four different CpG ODNs for stimulation of the TLR9 receptor and their respective control ODNs. It comprises agonists of the A-class (ODN 2216), B-class (ODN 2006), C-class (ODN 2395) and P-class (ODN 21798). |
性能供应商 | Miltenyi |
背景 | TLR9 is a prominent member of the toll-like-receptor (TLR) family recognizing pathogen-associated molecular patterns. TLR9 recognizes specifically unmethylated CpG motifs in bacterial DNA leading to activation of immune cells1,2. These effects can be mimicked by short synthetical oligodeoxynucleotides (ODNs) containing unmethylated CpG motifs3. |