产品中心
当前位置：首页>产品中心Anti-RASGEF1B/PE-Cy3
货号： bs-21162R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-21162R-PE-Cy3
- 英文名称
- Anti-RASGEF1B/PE-Cy3
- 中文名称
- PE-Cy3标记的RASGEF1B蛋白抗体
- 别 名
- GPIG4.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 G蛋白信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Pig, Cow, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 55kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human RASGEF1B
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
RASGEF1B (RasGEF Domain Family Member 1B) is a Protein Coding gene. Diseases associated with RASGEF1B include Chromosome 4Q21 Deletion Syndrome. GO annotations related to this gene include guanyl-nucleotide exchange factor activity and Ras guanyl-nucleotide exchange factor activity. An important paralog of this gene is RASGEF1C.
Function:
Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, it doesnt seems to activate other Ras family proteins (in vitro).
Subunit:
Interacts with Ras family proteins (By similarity). Interacts with CCDC124 during cytokinesis.
DISEASE:
Up-regulated in macrophages stimulated with IFNG, GPI-mucins or bacterial lipopolysaccharides (LPS).
Similarity:
Contains 1 N-terminal Ras-GEF domain.
Contains 1 Ras-GEF domain.
Database links:Entrez Gene: 153020Human
SwissProt: Q0VAM2Human
Unigene: 591696Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.