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货号： bs-12763R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12763R-PE-Cy3
- 英文名称
- Anti-VPS11/PE-Cy3
- 中文名称
- PE-Cy3标记的液泡蛋白分选蛋白11抗体
- 别 名
- END1; HGNC:14583; hVPS11; PEP5; PP3476; RING finger protein 108; RNF108; Vacuolar protein sorting 11 (yeast homolog); Vacuolar protein sorting 11 (yeast); Vacuolar protein sorting 11 homolog (S. cerevisiae); Vacuolar protein sorting 11 homolog; Vacuolar protein sorting associated protein 11 homolog; Vacuolar protein sorting protein 11; Vacuolar protein sorting-associated protein 11 homolog; vps11; VPS11_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 转运蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 108kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human VPS11
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Function:
May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes.
Subcellular Location:
Late endosome membrane. Lysosome membrane. Cytoplasmic vesicle.
Tissue Specificity:
Ubiquitous. Expression was highest in heart and low in lung.
Similarity:
Belongs to the VPS11 family.
Contains 1 clathrin repeat.
Contains 1 RING-type zinc finger.
Database links:Entrez Gene: 489374Dog
Entrez Gene: 55823Human
Entrez Gene: 71732Mouse
Entrez Gene: 315600Rat
Omim: 608549Human
SwissProt: Q9H270Human
SwissProt: Q91W86Mouse
Unigene: 234282Human
Unigene: 295013Mouse
Unigene: 2637Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.