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货号： bs-9590R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-9590R-PE-Cy3
- 英文名称
- Anti-PDE4B/PE-Cy3
- 中文名称
- PE-Cy3标记的磷酸二酯酶4B抗体
- 别 名
- 5-cyclic phosphodiesterase 4B; cAMP-specific 3; cAMP-specific 3,5-cyclic phosphodiesterase 4B; cAMP-specific 35-cyclic Phosphodiesterase 4B; cAMP-specific phosphodiesterase-4 B isoform; DKFZp686F2182; DPDE4; dunce-like phosphodiesterase E4; MGC126529; OTTHUMP00000010652; OTTHUMP00000010653; OTTHUMP00000010654; OTTHUMP00000010656; OTTHUMP00000232365; PDE 4B; PDE IVB; PDE32; Pde4b; PDE4B_HUMAN; PDE4B5; PDEIVB; Phosphodiesterase 4B; Phosphodiesterase 4B cAMP specific; Phosphodiesterase 4B, cAMP specific (phosphodiesterase E4 dunce homolog, Drosophila); Phosphodiesterase-4B cAMP-specific (dunce (Drosophila)-homolog); Phosphodiesterase-4B cAMP-specific.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 107kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PDE4B
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
Function:
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.
Tissue Specificity:
Expressed in brain, heart, lung and skeletal muscle.
Similarity:
Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
Database links:Entrez Gene: 5142Human
Entrez Gene: 18578Mouse
Entrez Gene: 24626Rat
Omim: 600127Human
SwissProt: Q07343Human
SwissProt: P14646Rat
Unigene: 198072Human
Unigene: 20181Mouse
Unigene: 37733Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.