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货号： bs-12589R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12589R-PE-Cy3
- 英文名称
- Anti-PDE9A/PE-Cy3
- 中文名称
- PE-Cy3标记的磷酸二酯酶9A抗体
- 别 名
- 5-cyclic phosphodiesterase 9A; cGMP specific 3 5 cyclic phosphodiesterase type 9; CGMP-specific 35-cyclic phosphodiesterase type 9; FLJ90181; High affinity cGMP-specific 3; High-affinity cGMP-specific 35-cyclic phosphodiesterase 9A; HSPDE9A2; OTTHUMP00000109399; PDE 9A; Pde9a; PDE9A_HUMAN; Phosphodiesterase 9A; phosphodiesterase PDE9A21.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 70-73kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PDE9A
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. The encoded protein plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function:
Hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes.
Subcellular Location:
Cytoplasm. Endoplasmic reticulum; Cell projection > ruffle membrane. Cytoplasm > perinuclear region and Cell projection > ruffle membrane. Cytoplasm > perinuclear region. Golgi apparatus. Endoplasmic reticulum.
Tissue Specificity:
Expressed in all tissues examined (testis, brain, small intestine, skeletal muscle, heart, lung, thymus, spleen, placenta, kidney, liver, pancreas, ovary and prostate) except blood. Highest levels in brain, heart, kidney, spleen, prostate and colon. Isoform PDE9A12 is found in prostate.
Similarity:
Belongs to the cyclic nucleotide phosphodiesterase family. PDE9 subfamily.
Database links:Entrez Gene: 5152Human
Entrez Gene: 18585Mouse
Entrez Gene: 191569Rat
GenBank: NP_001001567.1Human
Omim: 602973Human
SwissProt: O76083Human
SwissProt: O76083-2Human
SwissProt: O70628Mouse
Unigene: 473927Human
Unigene: 10812Mouse
Unigene: 20981Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.