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货号： bs-19698R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19698R-PE-Cy3
- 英文名称
- Anti-QSOX2/PE-Cy3
- 中文名称
- PE-Cy3标记的巯基氧化酶2抗体
- 别 名
- DKFZp762A2013; Neuroblastoma-derived sulfhydryl oxidase; QSCN6L1; QSOX2; QSOX2_HUMAN; Quiescin Q6 like 1; Quiescin Q6 sulfhydryl oxidase 2; Quiescin Q6-like protein 1; SOXN; Sulfhydryl oxidase 2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 神经生物学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 76kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human QSOX2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
QSOX2 is a member of the sulfhydryl oxidase/quiescin-6 (Q6) family (QSOX1; MIM 603120) that regulates the sensitization of neuroblastoma cells for IFN-gamma (IFNG; MIM 147570)-induced cell death (Wittke et al., 2003 [PubMed 14633699]).[supplied by OMIM, Jun 2009]
Function:
Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. Also seems to play a role in regulating the sensitization of neuroblastoma cells for interferon-gamma-induced apoptosis.
Subcellular Location:
Membrane. Secreted. Cell membrane. Nucleus membrane. Seems to be predominantly targeted to the nuclear and outer plasma membrane.
Tissue Specificity:
Expressed in pancreas, brain, placenta, kidney, heart and fetal tissues. Weakly expressed in lung, liver and skeletal muscles.
Similarity:
Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
Contains 1 ERV/ALR sulfhydryl oxidase domain.
Contains 1 thioredoxin domain.
Database links:Entrez Gene: 788063Cow
Entrez Gene: 607571Dog
Entrez Gene: 101144374Gorilla
Entrez Gene: 169714Human
Entrez Gene: 227638Mouse
Entrez Gene: 100020838Opossum
Entrez Gene: 681023Rat
Omim: 612860Human
SwissProt: Q6ZRP7Human
SwissProt: Q3TMX7Mouse
Unigene: 657864Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.