产品中心
当前位置：首页>产品中心Anti-SF3A1/PE-Cy3
货号： bs-19676R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19676R-PE-Cy3
- 英文名称
- Anti-SF3A1/PE-Cy3
- 中文名称
- PE-Cy3标记的选择性剪接因子3亚基1抗体
- 别 名
- Pre mRNA processing 21; Pre mRNA splicing factor SF3a; PRP21; PRPF21; SAP 114; SAP114; sf3a1; SF3A1_HUMAN; SF3A120; Spliceosome associated protein 114; Spliceosome-associated protein 114; Splicing factor 3 subunit 1; Splicing factor 3a subunit 1 120kDa; Splicing factor 3a subunit 1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 89kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SF3A1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a subunit of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer is a component of the mature U2 small nuclear ribonucleoprotein particle (snRNP). U2 small nuclear ribonucleoproteins play a critical role in spliceosome assembly and pre-mRNA splicing. [provided by RefSeq, Aug 2014]
Function:
Subunit of the splicing factor SF3A required for A complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the E complex.
Subunit:
Nucleus.
Tissue Specificity:
Ubiquitously expressed.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity:
Contains 2 SURP motif repeats.
Contains 1 ubiquitin-like domain.
Database links:Entrez Gene: 10291Human
Entrez Gene: 67465Mouse
Omim: 605595Human
SwissProt: Q15459Human
SwissProt: Q8K4Z5Mouse
Unigene: 406277Human
Unigene: 505597Human
Unigene: 156914Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.