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货号： bs-6510M-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-6510M-PE-Cy3
- 英文名称
- Anti-ABH8/PE-Cy3
- 中文名称
- PE-Cy3标记的AlkB同源蛋白8抗体
- 别 名
- ABH8; alkB alkylation repair homolog 8 (E. coli); alkB alkylation repair homolog 8; AlkB homologue 8; ALKB8_HUMAN; ALKBH8; Alkylated DNA repair protein alkB homolog 8; Probable alpha-ketoglutarate-dependent dioxygenase ABH8; S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤
- 抗体来源
- Mouse
- 克隆类型
- Polyclonal
- 交叉反应
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 75kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ABH8
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis.
Function:
Catalyzes the methylation of 5-carboxymethyl uridine to5-methylcarboxymethyl uridine at the wobble position of theanticodon loop in tRNA. Catalyzes the last step in the formation of5-methylcarboxymethyl uridine at the wobble position of theanticodon loop in target tRNA. Has a preference for tRNA(Arg) andtRNA(Glu), and does not bind tRNA(Lys). Required for normalsurvival after DNA damage. May inhibit apoptosis and promote cellsurvival and angiogenesis.
Subunit:
Interacts with TRMT112.
Subcellular Location:
Cytoplasm. Nucleus. Note=Predominantlycytoplasmic.
Tissue Specificity:
Widely expressed, with highest expression inspleen, followed by pancreas and lung.
Similarity:
Belongs to the alkB family.
Contains 1 Fe2OG dioxygenase domain.
Contains 1 RRM (RNA recognition motif) domain.
Database links:Entrez Gene: 91801 Human
Entrez Gene: 67667 Mouse
Entrez Gene: 366783 Rat
Omim: 613306 Human
SwissProt: Q96BT7 Human
SwissProt: Q80Y20 Mouse
Unigene: 503763 Human
Unigene: 116968 Mouse
Unigene: 440994 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.