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货号： bs-2430R 基本售价： 780.0 元 规格： 50ul
- 规格：50ul
- 价格：780.00元
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-2430R
- 英文名称
- Apelin Receptor
- 中文名称
- 血管紧张素II受体样蛋白1抗体
- 别 名
- APJ receptor; AGTR L1; AGTRL 1; AGTRL1; Angiotensin II receptor like 1; Angiotensin receptor like 1; Apelin receptor; APJ; B78; FLJ90771; G protein coupled receptor APJ; GPCR34; HG 11; HG11; MGC45246; MSR; msr/apj; Aplnr; Agtrl1; APLNR; FLJ96609; APJ_HUMAN.
- Specific References (2) | bs-2430R has been referenced in 2 publications.[IF=1.61] Ustunel, Ismail, et al. "The effects of water immersion and restraint stress on the expressions of apelin, apelin receptor (APJR) and apoptosis rate in the rat heart." Acta Histochemica (2014) IHC-P ; Rat.PubMed:24411164[IF=1.64] Izgüt-Uysal, V. N., et al. "The effect of apelin on the functions of peritoneal macrophages." Physiological research (2017). IHC ; Rat.PubMed:28248533
- 规格价格
- 50ul/780元购买 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 50ul 100ul 200ul
- 研究领域
- 心血管 细胞生物 免疫学 G蛋白偶联受体 G蛋白信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Rabbit,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 Flow-Cyt=1μg/Test （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 42kDa
- 细胞定位
- 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Apelin receptor:41-140/380 <Cytoplasmic>
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq
Function:
Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.
Subcellular Location:
Cell membrane.
Tissue Specificity:
Widely expressed in the brain, in glial cells, astrocytes and neuronal subpopulations, as well as in the spleen, thymus, ovary, small intestine and colon.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
SWISS:
P35414
Gene ID:
187
Database links:Entrez Gene: 429337Chicken
Entrez Gene: 615435Cow
Entrez Gene: 187Human
Entrez Gene: 23796Mouse
Entrez Gene: 83518Rat
Omim: 600052Human
SwissProt: P35414Human
SwissProt: Q9WV08Mouse
SwissProt: Q9JHG3Rat
Unigene: 438311Human
Unigene: 29368Mouse
Unigene: 7965Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
- 产品图片
Sample:
Cerebrum(mouse) Lysate at 40 ug
heart(mouse) Lysate at 40 ug
Primary: Anti-Apelin receptor (bs-2430R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 42 kD
Observed band size: 52 kD
Positive control(blue): mouse Splenocytes
Isotype Antibody (orenge): Rabbit IgG, Dilution: 1ug in 100 u1 X PBS containing 0.5% BSA
Secondary Antibody(light blue): Goat anti-rabbit IgG-FITC,Dilution: 1:200 in 1 X PBS containing 0.5% BSA
Primary Antibody catalog number (green): bs-2430R, Dilution: 1ug in 100ul 1X PBS containing 0.5% BSA