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货号： bs-19211R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19211R-PE-Cy3
- 英文名称
- Anti-Neurexophilin 3/PE-Cy3
- 中文名称
- PE-Cy3标记的神经外营养蛋白3抗体
- 别 名
- KIAA1159; Neurexophilin-3; NPH3; Nxph3;NXPH-3; NXPH3_HUMAN; UNQ687/PRO1327.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 28kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Neurexophilin 3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Neurexophilin-1-3 are secreted proteins that are thought to function as signaling molecules which specifically bind to target proteins, such as neurexin I Alpha(a protein that promotes adhesion between dendrites and axons), and are essential for proper neurotransmitter release. While Neurexophilin-1 is located primarily in spleen tissue, Neurexophilin-2 is expressed primarily in kidney and both Neurexophilin-2 and Neurexophilin-3 are highly expressed in brain. Defects in the gene encoding Neurexophilin-1 may be associated with schizophrenia, a mental disorder characterized by an abnormal perception of reality.
Function:
May be signaling molecules that resemble neuropeptides. Ligand for alpha-neurexins.
Subcellular Location:
Secreted.
Tissue Specificity:
Highest level in brain.
Post-translational modifications:
May be proteolytically processed at the boundary between the N-terminal non-conserved and the central conserved domain in neuron-like cells.
Similarity:
Belongs to the neurexophilin family.
Database links:Entrez Gene: 11248Human
Entrez Gene: 104079Mouse
Entrez Gene: 59315Rat
Omim: 604636Human
SwissProt: O95157Human
SwissProt: Q91VX5Mouse
SwissProt: Q9Z2N5Rat
Unigene: 55069Human
Unigene: 22970Mouse
Unigene: 19736Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.