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货号： bs-10935R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-10935R-PE-Cy3
- 英文名称
- Anti-CHKL/PE-Cy3
- 中文名称
- PE-Cy3标记的乙醇胺激酶β抗体
- 别 名
- Ethanolamine kinase beta; CHETK; Chetk-beta; CHKB; Chkb choline kinase beta; Chkb protein; CHKB_HUMAN; CHKL; Choline kinase beta; Choline kinase-like; Choline kinase-like protein; Choline/ethanolamine kinase; choline/ethanolamine kinase beta; Choline/ethanolamine kinase, beta; CK; CK/EK; CK/EK-beta; CKB; CKEKB; EK; EKB; Ethanolamine kinase; Ethanolamine kinase beta; Ethanolamine kinase, beta.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 信号转导 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 45kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CHKL
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Choline kinase (CK) and ethanolamine kinase (EK) catalyzethe phosphorylation of choline/ethanolamine tophosphocholine/phosphoethanolamine. This is the first enzyme in thebiosynthesis of phosphatidylcholine/phosphatidylethanolamine in allanimal cells. The highly purified CKs from mammalian sources andtheir recombinant gene products have been shown to have EK activityalso, indicating that both activities reside on the same protein.The choline kinase-like protein encoded by CHKL belongs to thecholine/ethanolamine kinase family; however, its exact function isnot known. Read-through transcripts are expressed from this locusthat include exons from the downstream CPT1B locus. [provided byRefSeq, Jun 2009].
Function:
Has a key role in phospholipid biosynthesis. Catalyzes the first step in phosphatidylethanolamine biosynthesis. Phosphorylates ethanolamine, and can also act on choline (in vitro). Has higher activity with ethanolamine. May not significantly contribute to in vivo phosphatidylcholine biosynthesis.
Subunit:
Homodimer, and heterodimer with CHKA.
Similarity:
Belongs to the choline/ethanolamine kinase family.
Database links:Entrez Gene: 1120Human
Omim: 612395Human
SwissProt: Q9Y259Human
Unigene: 654827Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.