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货号: bs-19024R-PE-Cy3 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-19024R-PE-Cy3
- 英文名称
- Anti-NARS2/PE-Cy3
- 中文名称
- PE-Cy3标记的天冬氨酰tRNA连接酶2抗体
- 别 名
- AI875199; AsnRS; Asparagine tRNA ligase 2; Asparagine tRNA ligase 2 mitochondrial; Asparagine tRNA ligase; Asparaginyl tRNA synthetase 2; Asparaginyl tRNA synthetase 2 mitochondrial; FLJ23441; MGC125113; MGC41336; NARS 2; Probable asparaginyl tRNA synthetase; Probable asparaginyl tRNA synthetase mitochondrial; RGD1305145; SLM5.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 信号转导 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 52kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NARS2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
SLM5 (mitochondrial asparaginyl-tRNA synthetase, Asparagine-tRNA ligase) is a mitochondrial protein encoded by the human gene NARS2. AsnRS belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl tRNA synthetases (aaRS) are enzymes that catalyze the esterification of a specific amino acid or its precursor to its compatible cognate tRNA to form an aminoacyl-tRNA. The synthetase first binds ATP and the corresponding amino acid or its precursor to form an aminoacyl-adenylate and release inorganic pyrophosphate (PPi). The adenylate-aaRS complex then binds the appropriate tRNA molecule, and the amino acid is transferred from the aa-AMP to either the 2- or 3-OH of the last tRNA base (A76) at the 3-end. Some synthetases also mediate a proofreading reaction to ensure high fidelity of tRNA charging; if the tRNA is found to be improperly charged, the aminoacyl-tRNA bond is hydrolyzed. SLM5 acts to attach asparagine residues to its cognate tRNA.
Subcellular Location:
Mitochondrion matrix.
Similarity:
Belongs to the class-II aminoacyl-tRNA synthetase family.
Database links:Entrez Gene: 79731Human
SwissProt: Q96I59Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.