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货号： bs-18993R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18993R-PE-Cy3
- 英文名称
- Anti-NAALADL2/PE-Cy3
- 中文名称
- PE-Cy3标记的NAALADL2蛋白抗体
- 别 名
- Glutamate carboxypeptidase II type non peptidase homologue; Inactive N acetylated alpha linked acidic dipeptidase like protein 2; Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2; N acetylated alpha linked acidic dipeptidase like 2; NAALADase L2; NAALADL 2; NAALADL2; NADL2_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Saccharomyces cerevisiae
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 38kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NAALADL2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
NAALADL2 is a 795 amino acid single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. Existing as two alternatively spliced isoforms, NAALADL2 is expressed at highest levels in placenta and kidney, and has also been observed in certain embryonic tissues. NAALADL2 may be catalytically inactive. The gene encoding NAALADL2 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Function:
May be catalytically inactive.
Subcellular Location:
Membrane.
Tissue Specificity:
Expressed at higher level in kidney and placenta. In embryo, it is mainly confined to duodenal and stomach endoderm, mesonephros, metanephros and pancreas.
Similarity:
Belongs to the peptidase M28 family. M28B subfamily.
Database links:Entrez Gene: 254827Human
Entrez Gene: 635702Mouse
Entrez Gene: 499583Rat
Omim: 608806Human
SwissProt: Q58DX5Human
Unigene: 565848Human
Unigene: 603646Human
Unigene: 660010Human
Unigene: 448351Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.