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货号： bs-18985R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18985R-PE-Cy3
- 英文名称
- Anti-N4BP2/PE-Cy3
- 中文名称
- PE-Cy3标记的E3泛素连接酶NEDD4结合蛋白2抗体
- 别 名
- B3BP; BCL 3 binding protein; BCL3 binding protein; FLJ10680; KIAA1413; Nedd4 binding protein 2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 神经生物学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 199kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human N4BP2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a protein containing a polynucleotide kinase domain (PNK) near the N-terminal region, and a Small MutS Related (Smr) domain near the C-terminal region. The encoded protein can bind to both B-cell leukemia/lymphoma 3 (BCL-3) and neural precursor cell expressed, developmentally downregulated 4, (Nedd4) proteins. This protein binds and hydrolyzes ATP, may function as a 5-polynucleotide kinase, and has the capacity to be a ubiquitylation substrate. This protein may play a role in transcription-coupled DNA repair or genetic recombination. [provided by RefSeq, Jul 2008]
Function:
Has 5-polynucleotide kinase and nicking endonuclease activity. May play a role in DNA repair or recombination.
Subunit:
Binds NEDD4 By similarity. Binds BCL3 and CREBBP.
Subcellular Location:
Cytoplasm
Post-translational modifications:
Ubiquitinated; this targets the protein for degradation by the proteasome
Similarity:
Contains 1 CUE domain.
Contains 1 Smr domain.
Database links:Entrez Gene: 55728Human
SwissProt: Q86UW6Human
Unigene: 396494Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.