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货号： bs-18090R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18090R-PE-Cy3
- 英文名称
- Anti-HSPC210/GSK3beta interaction protein/PE-Cy3
- 中文名称
- PE-Cy3标记的GSK3β相互作用蛋白抗体
- 别 名
- C14ORF129; Chromosome 14 open reading frame 129; GSK3-beta interaction protein; GSK3beta interaction protein; GSKIP; GSKIP; GSKIP_HUMAN; MGC4945; UPF0279.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 信号转导 细胞周期蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cynomolgus Monkey
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 16kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human HSPC210/GSK3beta interaction protein
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Detected in heart, brain, placenta, liver, skeletal muscle, kidney, testis, lung and pancreas.
Similarity:
Belongs to the UPF0279 family.
Database links:Entrez Gene: 51527Human
Entrez Gene: 66787Mouse
Entrez Gene: 362778Rat
SwissProt: Q9P0R6Human
SwissProt: Q8BGR8Mouse
SwissProt: Q5PPI3Rat
Unigene: 728153Human
Unigene: 248019Mouse
Unigene: 3701Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.