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货号： bs-23760R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-23760R
- 英文名称
- IL-28
- 中文名称
- 白细胞介素28抗体
- 别 名
- Interleukin 28/Interferon lambda-2; Interleukin 28A; IL28A; IFNL2; IL-28A; EG330496; Ifnl2; IFNL2_HUMAN.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- WB=1:200-2000 ELISA=1:5000-20000 IHC-P=1:400-800 IHC-F=1:400-800 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 20kDa
- 细胞定位
- 分泌型蛋白
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human IL-28:131-180/196
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]
Function:
Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium.
Subcellular Location:
Secreted.
Similarity:
Belongs to the lambda interferon family.
SWISS:
Q8IZJ0
Gene ID:
282616
Database links:Entrez Gene: 282616 Human
Entrez Gene: 330496 Mouse
Omim: 607401 Human
SwissProt: Q8IZJ0 Human
SwissProt: Q4VK74 Mouse
Unigene: 567792 Human
Unigene: 454510 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
- 产品图片
Sample:
MCF-7(human) cell Lysate at 30 ug
Primary: Anti-IL-28 (bs-23760R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 20kD
Observed band size: 20 kD
Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:100
Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:100
Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:100
Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:100
Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:100