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货号： bs-6010R-HRP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-6010R-HRP
- 英文名称
- Anti-GTPBP4/HRP
- 中文名称
- 辣根过氧化物酶标记的GTP结合蛋白4抗体（慢性肾功能衰竭蛋白）
- 别 名
- Chronic renal failure gene protein; CRFG; G protein binding protein CRFG; GTP binding protein 4; NGB; NOG1; Nucleolar GTP binding protein 1; NOG1_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 信号转导 结合蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 74kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GTPBP4/CRFG
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. Active in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. [Entrez Gene]
Function:
Involved in the biogenesis of the 60S ribosomal subunit
Subcellular Location:
Nucleus, nucleolus.
Similarity:
Belongs to the GTP1/OBG family. NOG subfamily.
Database links:Entrez Gene: 23560 Human
Entrez Gene: 69237 Mouse
Entrez Gene: 114300 Rat
SwissProt: Q9BZE4 Human
SwissProt: Q99ME9 Mouse
SwissProt: Q99P77 Rat
Unigene: 215766 Human
Unigene: 41800 Mouse
Unigene: 96111 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.