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货号： bs-6045R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-6045R-PE-Cy3
- 英文名称
- Anti-DPP2/PE-Cy3
- 中文名称
- PE-Cy3标记的溶酶体丝氨酸蛋白酶DPP2抗体
- 别 名
- Dipeptidyl aminopeptidase II; Dipeptidyl peptidase 7; Dipeptidyl peptidase II; DPP II; DPP2; DPP7; DPPII; QPP; Quiescent cell proline dipeptidase.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 激酶和磷酸酶
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 52kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human DPP2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
DPP2 is a serine protease found most abundantly in the lysosome. There is also a non-lysosomal membrane-associated form of DPP2 reported in the rat brain (DPP-II-M), and a soluble form (DPP-II-S). First discovered as an enzyme involved in the terminal steps of protein degradation, and later as an enzyme involved in cell growth and quiescence, DPP2 cleaves N-terminal dipeptides and tripeptides from proteins. DPP2 has a preference for proline in the P1 position, and processes the tripeptides generated by DPP1 (which is unable to cleave if proline is in the P1 position). Some tumor cell lines express elevated DPP2 levels, and serum levels of DPP2 are elevated in some cancer patients, making DPP2 a potential tumor marker. DPP2 levels have been also been reported to be elevated in the cerebral spinal fluid from Parkinson’s patients.
Function:
Plays an important role in the degradation of some oligopeptides.
Subunit:
Homodimer.
Subcellular Location:
Lysosome. Cytoplasmic vesicle. Secreted.
Tissue Specificity:
Detected in seminal plasma (at protein level).
Post-translational modifications:
N-glycosylated.
Similarity:
Belongs to the peptidase S28 family.
Database links:Entrez Gene: 29952 Human
Entrez Gene: 83768 Mouse
Entrez Gene: 83799 Rat
Omim: 610537 Human
SwissProt: Q9UHL4 Human
SwissProt: Q9ET22 Mouse
SwissProt: Q9EPB1 Rat
Unigene: 37916 Human
Unigene: 3363 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.