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货号： bs-7577R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-7577R-PE-Cy3
- 英文名称
- Anti-SLC25A6/PE-Cy3
- 中文名称
- PE-Cy3标记的线粒体载体腺嘌呤核苷酸转运蛋白6抗体
- 别 名
- Adenine nucleotide translocator 3; ADP ATP carrier protein 3; ADP ATP carrier protein isoform T2; ADP ATP carrier protein liver; ADP/ATP translocase 3; ADP/ATP translocator of liver; ANT 3; ANT3; ANT3Y; MGC17525; Solute carrier family 25 (mitochondrial carrier adenine nucleotide translocator) member 6;Solute carrier family 25 member 6; ADT3_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 转录调节因子 线粒体
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Zebrafish, Sheep,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 33kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SLC25A6 (65-100aa)
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
SLC25A6 (solute carrier family 25, member A6) participates in the exchange of ADP and ATP across the mitochondrial inner membrane. It may be involved in the formation of the permeability transition pore complex (PTPC), a multiprotein complex built up at the contact site between the inner and the outer mitochondrial membranes. Opening of the PTPC causes massive swelling of mitochondria, rupture of the outer membrane and release of intermembrane components that induce apoptosis.
Function:
Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
Subunit:
Found in a complex with ARL2, ARL2BP and SLC25A6. Homodimer. Interacts with influenza A virus PB1-F2 protein and HIV-1 Vpr.
Subcellular Location:
Mitochondrion inner membrane; Multi-pass membrane protein.
Similarity:
Belongs to the mitochondrial carrier family.
Contains 3 Solcar repeats.
Database links:Entrez Gene: 293 Human
Entrez Gene: 374072 ChickenEntrez Gene: 282480 Cow
Entrez Gene: 67582 Mouse
Entrez Gene: 498885 Rat
Entrez Gene: 566370 Zebrafish
Omim: 300151 Human
Omim: 403000 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.