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货号： bs-6382R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-6382R-PE-Cy3
- 英文名称
- Anti-PTK5/FRK/PE-Cy3
- 中文名称
- PE-Cy3标记的胃肠道相关酪氨酸激酶抗体（蛋白酪氨酸激酶5）
- 别 名
- Beta cell Src homology tyrosine kinase; BSK; BSK/IYK; C85044; Frk; Frk fyn related kinase; FRK_HUMAN; FYN related kinase; FYN-related kinase; GASK; Gastrointestinal associated kinase; Gastrointestinal associated tyrosine kinase; GTK; Intestine tyrosine kinase; Nuclear tyrosine protein kinase RAK; Protein-tyrosine kinase 5; PTK5; RAK; Tyrosine protein kinase FRK; Tyrosine-protein kinase FRK.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 细胞周期蛋白 激酶和磷酸酶
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 58kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human FRK/PTK5
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. [provided by RefSeq, Jul 2008].
Function:
Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on Tyr-336, which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor.
Subunit:
Interacts (via the SH3-domain) with PTEN. Interacts with RB1.
Subcellular Location:
Cytoplasm. Nucleus. Note=Predominantly found in the nucleus, with a small fraction found in the cell periphery.
Tissue Specificity:
Predominantly expressed in epithelial derived cell lines and tissues, especially normal liver, kidney, breast and colon.
Similarity:
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
Database links:Entrez Gene: 2444Human
Entrez Gene: 14302Mouse
Entrez Gene: 79209Rat
Omim: 606573Human
SwissProt: P42685Human
SwissProt: Q922K9Mouse
SwissProt: Q62662Rat
Unigene: 89426Human
Unigene: 332432Mouse
Unigene: 10556Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.