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货号： bs-9029R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-9029R-PE-Cy3
- 英文名称
- Anti-PAPSS1/PE-Cy3
- 中文名称
- PE-Cy3标记的腺苷酸硫酸激酶1抗体
- 别 名
- Adenylyl-sulfate kinase; Adenylylsulfate 3-phosphotransferase; APS kinase; ATP-sulfurylase; ATPSK 1; ATPSK1; Bifunctional 3 phosphoadenosine 5 phosphosulfate synthetase 1; PAPS synthase 1; PAPS synthetase 1; PAPS1_HUMAN; PAPSS 1; PAPSS; PAPSS1; SAT; SK 1; SK1; Sulfate adenylate transferase; Sulfurylase kinase 1; 3 prime phosphoadenosine 5 prime phosphosulfate synthase 1; 3 phosphoadenosine 5 phosphosulfate synthase 1; 3-phosphoadenosine-5-phosphosulfate synthase; Adenosine-5-phosphosulfate 3-phosphotransferase.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 69kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PAPSS1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Three-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS) is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes (Xu et al., 2000 [PubMed 10679223]). SULTs catalyze the sulfate conjugation of many endogenous and exogenous compounds, including drugs and other xenobiotics. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2 (MIM 603005).[supplied by OMIM, Mar 2008].
Function:
Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway. Also involved in the biosynthesis of sulfated L-selectin ligands in endothelial cells.
Tissue Specificity:
Expressed in testis, pancreas, kidney, thymus, prostate, ovary, small intestine, colon, leukocytes and liver. Also expressed in high endothelial venules (HEV) cells and in cartilage.
Similarity:
In the N-terminal section; belongs to the APS kinase family.
In the C-terminal section; belongs to the sulfate adenylyltransferase family.
Database links:Entrez Gene: 504439Cow
Entrez Gene: 9060Human
Entrez Gene: 9061Human
Entrez Gene: 23971Mouse
Entrez Gene: 295443Rat
Omim: 603262Human
SwissProt: O43252Human
SwissProt: O95340Human
SwissProt: O88428Mouse
SwissProt: Q60967Mouse
Unigene: 368610Human
Unigene: 524491Human
Unigene: 203916Mouse
Unigene: 244912Mouse
Unigene: 3507Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.