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货号： bs-6273R-HRP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-6273R-HRP
- 英文名称
- Anti-ENO1+ENO2+ENO3/HRP
- 中文名称
- 辣根过氧化物酶标记的神经元，肌肉特异性烯醇化酶抗体
- 别 名
- ENO1 + ENO2 + ENO3; 2-phospho-D-glycerate hydro-lyase; Alpha-enolase; Beta-enolase; C-myc promoter-binding protein; Crystallin Tau, included; ENO1L1; Enolase 1, (alpha); Enolase 2 (gamma, neuronal); Enolase 2; Enolase 3 (beta, muscle); Enolase 3; Enolase alpha; Enolase, beta; Enolase, gamma; Enolase, muscle specific; Enolase, neuron specific; Enolase, nonneuronal, included; Gamma-enolase; GSD13; MBP-1; MPB1; MSE; Muscle-specific enolase; Neural enolase; Neuron-specific enolase; NNE; Non-neural enolase; NSE; Phosphpyruvate hydratase; Plasminogen-binding protein; Skeletal muscle enolase.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 染色质和核信号 信号转导 转录调节因子 激酶和磷酸酶 肿瘤细胞生物标志物 新陈代谢 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Pig, Cow, Horse,
- 产品应用
- WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 48kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ENO1+ENO2+ENO3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Enolase 1 is a multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.
Enolase 2 has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.
Enolase 3 appears to have a function in striated muscle development and regeneration.
Database links:Entrez Gene: 2023 Human
Entrez Gene: 2026 Human
Entrez Gene: 2027 Human
Entrez Gene: 13806 Mouse
Entrez Gene: 13807 Mouse
Entrez Gene: 13808 Mouse
Entrez Gene: 24333 Rat
Entrez Gene: 24334 Rat
Entrez Gene: 25438 Rat
Omim: 131360 Human
Omim: 131370 Human
Omim: 172430 Human
SwissProt: P06733 Human
SwissProt: P09104 Human
SwissProt: P13929 Human
SwissProt: P17182 Mouse
SwissProt: P17183 Mouse
SwissProt: P21550 Mouse
SwissProt: P04764 Rat
SwissProt: P07323 Rat
SwissProt: P15429 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. [provided by RefSeq, Jan 2011].