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货号： bs-8570R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-8570R-PE-Cy3
- 英文名称
- Anti-Neurogenin 1/PE-Cy3
- 中文名称
- PE-Cy3标记的神经元素1抗体
- 别 名
- AKA; Ath4c; bHLHa6; Class A basic helix-loop-helix protein 6; Helix loop helix protein mATH 4C; MATH4C; NeuroD3; Neurog 1; Neurog1; Neurogenic basic helix loop helix protein; Neurogenic basic-helix-loop-helix protein; Neurogenic differentiation 3; Neurogenic differentiation factor 3; Neurogenin-1; Neurogenin1; Ngn; NGN-1; Ngn1; NGN1_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 信号转导 干细胞 细胞类型标志物 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 26kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NGN1/Neurogenin 1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The neurogenin family of proteins belongs to the basic helix-loop-helix (bHLH) superfamily and consists of neurogenin 1, neurogenin 2 and neurogenin 3 (also designated ngn3). bHLH members are transcriptional regulators that determine cell fate. During mouse neurogenesis, Neurogenin 1 and Neurogenin 2 are expressed in distinct progenitor populations in the central and peripheral nervous systems. Targeted mutation analyses have shown that Neurogenin 1 is essential for the determination of neuronal precursors for proximal cranial sensory ganglia and that Neurogenin 2 is essential for the determination of precursors for epibranchial placode-derived sensory neurons. The gene which encodes Neurogenin 1 maps to human chromosome 5q23-q31.
Subunit:
Efficient DNA binding requires dimerization with another bHLH protein.
Subcellular Location:
Nucleus.
Tissue Specificity:
Expression restricted to the embryonic nervous system.
Similarity:
Contains 1 basic helix-loop-helix (bHLH) domain.
Database links:
UniProtKB/Swiss-Prot: Q92886.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.