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货号： bs-9624R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-9624R-PE-Cy3
- 英文名称
- Anti-MRPS4/PE-Cy3
- 中文名称
- PE-Cy3标记的线粒体核糖体蛋白S4抗体
- 别 名
- BRMS2; C15orf12; Chromosome 15 open reading frame 12; imp3; IMP3_HUMAN; Mitochondrial ribosomal protein S4; MRPS4; U3 small nucleolar ribonucleoprotein protein imp3; U3 snoRNP protein 3 homolog; U3 snoRNP protein imp3.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 心血管 细胞生物 免疫学 发育生物学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow, Horse, Rabbit, Guinea Pig,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 22kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human U3 small nucleolar ribonucleoprotein protein IMP3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Imp3, is a 184 amino acid protein that contains one S4 RNA-binding domain and is the mammalian homolog of the yeast Imp3 protein. Localized to the nucleus, Imp3 exists as a component of a heterotrimeric complex consisting of MPP10, Imp3 and Imp4 and, in this complex, plays a key role in early cleavage events during pre-18S ribosomal processing. The gene encoding Imp3 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.
Function:
Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.
Subunit:
Component of a heterotrimeric complex containing IMP3, IMP4 and MPHOSPH10. Interacts with MPHOSPH10.
Subcellular Location:
Nucleus, nucleolus.
Similarity:
Belongs to the ribosomal protein S4P family.
Contains 1 S4 RNA-binding domain.
Database links:Entrez Gene: 55272 Human
Entrez Gene: 102462 Mouse
Entrez Gene: 315697 Rat
Omim: 612980 Human
SwissProt: Q9NV31 Human
SwissProt: Q921Y2 Mouse
Unigene: 513043 Human
Unigene: 12864 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.