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货号： bs-4948R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-4948R-PE-Cy3
- 英文名称
- Anti-Bacillus anthraci protein/PE-Cy3
- 中文名称
- PE-Cy3标记的炭疽杆菌菌体蛋白抗体
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 免疫学 细菌及病毒
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Bacillusantci
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- Whole cell protein of Bacillus anthraci
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Bacillus anthracis is an aerobic spore forming bacterium that causes anthrax, an acute infectious disease of cattle, sheep, goats, camels, antelopes and other herbivores. Infection can occur in humans when they are exposed to infected animals or tissue from infected animals via three routes: cutaneous, inhalation and gastrointestinal. B. anthracis spores persist in the soil for many years as they are resistant to heat, cold, radiation, desiccation, and disinfectants. In vivo, B anthracis produces a polypeptide (polyglutamic acid) capsule that protects it from phagocytosis. The virulence factors of B anthracis are its capsule and three component toxin, both encoded on plasmids.
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
炭疽杆菌从损伤的皮肤、胃肠粘膜及呼吸道进入人体后，首先在局部繁殖，产生毒素而致组织及脏器发生出血性浸润、坏死和高度水肿，形成原发性皮肤炭疽、肠炭疽的肺炭疽等。当机体抵抗力降低时，致病菌即迅速沿淋巴管及血管向全身扩散，形成败血症和继发性脑膜炎。皮肤炭疽因缺血及毒素的作用，真皮的神经纤维发生变化，故病灶处常无明显的疼痛感。炭疽杆菌的毒素可直接损伤血管的内皮细胞，使血管壁的通透性增加，导致有效血容量减少，微循环灌注量下降，血液呈高凝状态，出现DIC和感染性休克。