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货号： bs-11043R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11043R-PE-Cy3
- 英文名称
- Anti-Bestrophin 4/PE-Cy3
- 中文名称
- PE-Cy3标记的卵黄状黄斑病蛋白4抗体
- 别 名
- BEST 4; BEST4; BEST-4; Bestrophin 4; Bestrophin4; Bestrophin-4; Vitelliform macular dystrophy 2 like 2; Vitelliform macular dystrophy 2 like protein 2; VMD2L2; BEST4_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 信号转导 通道蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 53kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Bestrophin 4
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Bestrophin-4 is a 473 amino acid member of the Bestrophin family of proteins. Members of the Bestrophin family are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels. Bestrophin-4 acts as a calcium-sensitive chloride channel located in the cell membrane. It is believed that Bestrophin-4 also acts as a channel for other physiologically significant anions, such as bicarbonate. Bestrophin-4 is predominantly expressed in the colon, but can be found at low levels in testis, placenta, trachea, spinal chord, lung and retina.
Function:
Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
Subcellular Location:
Cell membrane; Multi-pass membrane protein.
Tissue Specificity:
Predominantly found in colon and the weakly in fetal brain, spinal cord, retina, lung, trachea, testis and placenta.
Similarity:
Belongs to the bestrophin family.
Database links:Entrez Gene: 510542 Cow
Entrez Gene: 482521 Dog
Entrez Gene: 100052813 Horse
Entrez Gene: 266675 Human
Entrez Gene: 100345949 Rabbit
Entrez Gene: 689103 Rat
Omim: 607336 Human
SwissProt: Q8NFU0 Human
Unigene: 302513 Human
Unigene: 84672 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.