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货号： bs-11372R-PE-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11372R-PE-Cy3
- 英文名称
- Anti-Synaptogyrin 1/PE-Cy3
- 中文名称
- PE-Cy3标记的神经细胞囊泡循环蛋白1抗体
- 别 名
- SNG1_HUMAN;Synaptogyrin-1;Syngr1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 26kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Synaptogyrin 1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The synaptogyrin family of proteins are integral membrane proteins containing four transmembrane regions. Synaptogyrins are tyrosine-phosphorylated proteins with two neuronal isoforms (Synaptogyrin-1 and -3) and one ubiquitous isoform (Synaptogyrin-2). Synaptophysin and synaptogyrin represent the major constituents of synaptic vesicles. Synaptogyrin-1 is associated with presynaptic vesicles in neuronal cells. Synaptogyrin-2, also known as cellugyrin, has a tyrosine phosphorylated C-terminal cytoplasmic tail and is involved in the regulation of membrane traffic in non-neuronal cells. Synaptogyrin-3 is expressed mainly in brain and placenta. Synaptogyrin-4 is a 234 amino acid protein encoded by the SYNGR4 gene.
Function:
Involved in the regulation of short-term and long-term synaptic plasticity.
Subcellular Location:
Membrane; Multi-pass membrane protein. Melanosome. Cell junction, synapse. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Similarity:
Belongs to the synaptogyrin family.
Contains 1 MARVEL domain.
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
囊泡循环蛋白,Synaptogyrin又称p29，是均一分布于神经系统的突触囊泡蛋白，在神经元及神经内分泌细胞高度表达，它是酪氨酸激酶的一个重要的囊泡相关底物。synaptogyrin为多基因家族编码，异构体的cDNA序列同源性为32%～46％。人的囊泡循环蛋白 cDNA有一阅读框架，编码234个氨基酸，分子量约25,683Da，有四个跨膜域，N端与C端朝向囊泡的胞质面，无糖基化位点，蛋白分子胞浆尾的氨基酸序列与Syp有74％的同源性。