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货号： bs-8725R-PE 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-8725R-PE
- 英文名称
- Anti-A-Myb/PE
- 中文名称
- PE标记的AMYB蛋白抗体
- 别 名
- AMYB; MGC120059; MGC120061; Myb related protein A; Myb-like protein 1; Myb-related protein A; MYBA_HUMAN; MYBL1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 转录调节因子 b-淋巴细胞 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 79kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human A-Myb
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- Function:
Strong transcriptional activator; DNA-binding protein that specifically recognize the sequence 5-YAAC[GT]G-3. Could have a role in the proliferation and/or differentiation of neurogenic, spermatogenic and B-lymphoid cells.
Subunit:
Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL2.
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed in a variety of lymphoid and solid tumor lines cultured in vitro.
Similarity:
Contains 3 HTH myb-type DNA-binding domains.
Database links:Entrez Gene: 396158Chicken
Entrez Gene: 4603Human
Entrez Gene: 17864Mouse
Entrez Gene: 297783Rat
Omim: 159405Human
SwissProt: P52550Chicken
SwissProt: P10243Human
SwissProt: P51960Mouse
Unigene: 445898Human
Unigene: 218701Mouse
Unigene: 479Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.