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货号： bs-1314R 基本售价： 780.0 元 规格： 50ul
- 规格：50ul
- 价格：780.00元
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-1314R
- 英文名称
- Oxytocin R
- 中文名称
- 催产素受体(缩宫素受体)抗体
- 别 名
- Oxytocin R; OT R; OT-R; OTR 1; OTR; OTR1; OXT R; OXTR; Oxytocin receptor; OXYR_HUMAN.
- Specific References (2) | bs-1314R has been referenced in 2 publications.[IF=2.00] Zhang, Ying, et al. "Expression of oxytocin receptors in the uterine junctional zone in women with adenomyosis." Acta Obstetricia et Gynecologica Scandinavica (2015). IHC-P ; Human.PubMed:25627343[IF=2.15] Huang, Miaomaio, et al. "The abnormal expression of oxytocin receptors in the uterine junctional zone in women with endometriosis." Reproductive Biology and Endocrinology 15.1 (2017): 1. IHC-P ; Human.PubMed:28049501
- 规格价格
- 50ul/780元购买 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 50ul 100ul 200ul
- 研究领域
- 神经生物学 生长因子和激素 细胞膜受体 内分泌病
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 43kDa
- 细胞定位
- 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from mouse oxytocin receptor:325-388/388 <Cytoplasmic>
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. Oxytocin receptor has been reported in breast, central nervous system, heart, ovary, placenta, prostate, salivary gland, testis, uterus, and vessel.
Subcellular Location:
Cell membrane; Multi-pass membrane protein.
Similarity:
Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
SWISS:
P97926
Gene ID:
18430
Database links:Entrez Gene: 281371 Cow
Entrez Gene: 5021 Human
Entrez Gene: 18430 Mouse
Entrez Gene: 397092 Pig
Entrez Gene: 25342 Rat
Omim: 167055 Human
SwissProt: P56449 Cow
SwissProt: P30559 Human
SwissProt: P97926 Mouse
SwissProt: P32306 Pig
SwissProt: P70536 Rat
SwissProt: Q28756 Sheep
Unigene: 2820 Human
Unigene: 333310 Mouse
Unigene: 6841 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
OTR在人的子宫平滑肌细胞膜上有缩宫素受体，缩宫素引起子宫收缩的机制可能是通过激活缩宫素受体而实现的。经研究发现，缩宫素受体在外周组织和中枢神经系统内均有分布。缩宫素与不同组织、细胞上的缩宫素受体结合，通过多种信号转导途径而发挥作用。
- 产品图片
Sample:
Brain (Mouse) Lysate at 40 ug
Primary: Anti-Oxytocin R (bs-1314R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 43 kD
Observed band size: 53 kD
Tissue/cell: Human endometrium tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-Oxytocin R Polyclonal Antibody, Unconjugated(bs-1314R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining