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货号： bs-12851R-PE 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12851R-PE
- 英文名称
- Anti-SUV3L1/PE
- 中文名称
- PE标记的ATP依赖RNA解旋酶Supv3L1抗体
- 别 名
- 6330443E10Rik; ATP dependent RNA helicase SUPV3L1, mitochondrial; ATP-dependent RNA helicase SUPV3L1; EC 3.6.1.; MGC109049; mitochondrial; OTTHUMP00000019719; S. Cerevisiae suppressor of var 1 3 like 1; suppressor of var1 (S.cerevisiae) 3 like 1; Suppressor of var1 3 like 1 (S. cerevisiae); Suppressor of var1 3 like 1 (S. cerevisiae)(SUV3); Suppressor of var1 3 like 1; Suppressor of var1 3 like protein 1; Suppressor of var1 3-like protein 1; SUPV 3 L 1; SUPV3L1; SUV 3; SUV 3 L 1; SUV3; SUV3 like protein 1; SUV3-like protein 1; SUV3_HUMAN; SUV3L1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 细胞凋亡 结合蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 88kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SUV3L1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- Function:
Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3 overhang double-stranded RNA with a 3-to-5 directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5-to-3 direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.
Subcellular Location:
Nucleus. Mitochondrion matrix. Mitochondrion matrix > mitochondrion nucleoid.
Tissue Specificity:
Broadly expressed.
Similarity:
Belongs to the helicase family.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.
Database links:Entrez Gene: 6832Human
Entrez Gene: 338359Mouse
Entrez Gene: 294385Rat
Omim: 605122Human
SwissProt: Q8IYB8Human
SwissProt: Q80YD1Mouse
SwissProt: Q5EBA1Rat
Unigene: 106469Human
Unigene: 235898Mouse
Unigene: 19830Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.