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货号： bs-12640R-PE 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12640R-PE
- 英文名称
- Anti-SMNDC1/PE
- 中文名称
- PE标记的SMN相关蛋白抗体
- 别 名
- 30 kDa splicing factor SMNrp; MGC106917; MGC112663; SMN related protein; SMN-related protein; smndc1; SMNR; SPF30; SPF30_HUMAN; Splicing factor 30, survival of motor neuron-related; Survival motor neuron domain containing 1; Survival motor neuron domain containing protein 1; Survival motor neuron domain-containing protein 1; Survival of motor neuron related splicing factor 30; Survival of motor neuron-related-splicing factor 30.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 细胞凋亡 细胞周期蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 26kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SMNDC1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. [provided by RefSeq, Jul 2008]
Function:
Necessary for spliceosome assembly. Overexpression causes apoptosis.
Subcellular Location:
Nucleus speckle. Nucleus > Cajal body. Detected in nuclear speckles containing snRNP and in Cajal (coiled) bodies.
Tissue Specificity:
Detected at intermediate levels in skeletal muscle, and at low levels in heart and pancreas.
Similarity:
Belongs to the SMN family.
Contains 1 Tudor domain.
Database links:Entrez Gene: 520500Cow
Entrez Gene: 10285Human
Entrez Gene: 76479Mouse
Entrez Gene: 287768Rat
Entrez Gene: 572679Zebrafish
Omim: 603519Human
SwissProt: Q3T045Cow
SwissProt: O75940Human
SwissProt: Q8BGT7Mouse
SwissProt: Q4QQU6Rat
SwissProt: Q7ZV80Zebrafish
Unigene: 632093Human
Unigene: 313687Mouse
Unigene: 103854Rat
Unigene: 75917Zebrafish
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.