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货号： bs-7566R-HRP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-7566R-HRP
- 英文名称
- Anti-RHBDD3/HRP
- 中文名称
- 辣根过氧化物酶标记的垂体瘤细胞凋亡抗体
- 别 名
- C22orf3;HS984G1A;Pituitary tumor apoptosis;PTAG;RHBD3_HUMAN;RHBDD3;Rhomboid domain containing 3;Rhomboid domain-containing protein 3.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 细胞凋亡 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 40kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human RHBDD3 (101-200aa)
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
PTAG is a novel 386 amino acid multi-pass membrane protein that contains one UBA domain and augments drug-induced apoptosis. Cells lacking PTAG have a reduced apoptotic response, thereby causing a predisposition to cell malignancy and resistance to chemotherapeutic interventions, and PTAG plays a role in colorectal tumorigenesis as the majority of primary colorectal tumors lack the PTAG gene. Encoded by a gene located on human chromosome 22, PTAG is often co-expressed with EWS (ewing sarcoma breakpoint region 1), a gene located directly downstream of PTAG.
Subcellular Location:
Membrane; Multi-pass membrane protein (Potential).
Similarity:
Contains 1 UBA domain
Database links:Entrez Gene: 25807Human
Entrez Gene: 279766Mouse
Entrez Gene: 289753Rat
SwissProt: Q9Y3P4Human
SwissProt: Q8BP97Mouse
SwissProt: Q642B3Rat
Unigene: 106730Human
Unigene: 260866Mouse
Unigene: 9606Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
RHBDD3分子是一个全新的TLR信号途径的负向调控蛋白分子,是一个能够显著抑制自身免疫性疾病发生的效应分子,RHBDD3控制机体避免发生过度的免疫应答、防止自身免疫性疾病的发生具有重要意义。