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货号： bs-7900R-HRP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-7900R-HRP
- 英文名称
- Anti-CD20L/MS4A3/HRP
- 中文名称
- 辣根过氧化物酶标记的CD20样蛋白抗体（造血干细胞4跨膜蛋白3）
- 别 名
- CD20 antigen homolog; CD20 antigen like; CD20 antigen like protein; CD20 antigen-like protein; CD20L; hematopoietic cell 4 transmembrane protein; Hematopoietic-specific transmembrane protein 4; HTm4; IgE receptor beta subunit; Membrane-spanning 4-domains subfamily A member 3; Ms4a3; MS4A3_HUMAN; OTTHUMP00000235850; OTTHUMP00000235851; OTTHUMP00000235853.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 干细胞 细胞周期蛋白 激酶和磷酸酶 细胞类型标志物
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 23kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MS4A3/CD20L
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
MS4A3 is a member of the membrane-spanning 4A gene family and displays unique expression patterns among hematopoietic cells and nonlymphoid tissues. MS4A3 is likely to play a role in signal transduction and may function as a subunit associated with receptor complexes. Alternative splicing may result in multiple transcript variants; however, not all variants have been fully described.
Function:
Hematopoietic modulator for the G1-S cell cycle transition. Modulates the level of phosphorylation of cyclin-dependent kinase 2 (CDK2) through its direct binding to cyclin-dependent kinase inhibitor 3 (CDKN3/KAP).
Subunit:
Interacts with CDKN3. Interacts with CDKN3-CDK2 complexes through its binding to CDKN3; this interaction facilitates dissociation of cyclin A from CDKN3-CDK2 complexes.
Subcellular Location:
Endomembrane system; Multi-pass membrane protein (By similarity). Cytoplasm, perinuclear region (By similarity). Note=Located in the perinuclear area.
Tissue Specificity:
Expressed specifically in hematopoietic cells and tissues.
Similarity:
Belongs to the MS4A family.
Database links:Entrez Gene: 932Human
Omim: 606498Human
SwissProt: Q96HJ5Human
Unigene: 99960Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.