CD138+ Plasma Cell Iso.Kit, mouse
货号:
130-092-530 基本售价:
询价 规格:
EA
产品信息
概述货号 | 130-092-530 |
描述 | The CD138+ Plasma Cell Isolation Kit was developed for the isolation of CD138+CD45R(B220)low/–CD19low/– antibody-secreting plasma cells1 from spleen, lymph nodes, and bone marrow. |
性能供应商 | Miltenyi |
背景 | CD138 (Syndecan-1) is a heparan sulfate-rich integral membrane proteoglycan, which functions as a matrix receptor for interstitial collagens, fibronectin, and thrombospondin. CD138 is predominantly expressed on the surface of epithelial cells in mature mouse tissues.2 Its expression on cells of the B cell lineage correlates with their developmental stage, location, and adhesion. In mice, CD138 is expressed on pre-B and immature B lymphocytes in the bone marrow. It is lost when B cells emigrate into the periphery, is absent on circulating and peripheral B cells, and is re-expressed upon B cell differentiation into plasmablasts and plasma cells.3 |