Plasmacytoid Dendritic Cell Isolation Kit, mouse
货号:
130-107-093 基本售价:
询价 规格:
EA
产品信息
概述货号 | 130-107-093 |
描述 | The Plasmacytoid Dendritic Cell Isolation Kit is designed for the isolation of untouched mouse plasmacytoid dendritic cells (PDCs) from single-cell suspensions of lymphoid organs. |
性能供应商 | Miltenyi |
背景 | Freshly isolated PDCs express low levels of MHC class II and costimulatory molecules and are poor stimulators of T helper cells. Upon stimulation with bacterial DNA containing particular unmethylated CpG motifs (CpG-DNA) or upon viral challenge, they produce large amounts of type I IFN and acquire antigen-presenting capacity.1,2 PDCs can be directly identified in lymphoid and non-lymphoid organs by the specific expression of mPDCA-1 (murine plasmacytoid dendritic cell antigen-1).3 mPDCA-1 has been identified as bone marrow stromal antigen 2 (BST2).4 |