CD171 (L1CAM) MicroBead Kit, mouse
货号:
130-101-549 基本售价:
询价 规格:
EA
产品信息
概述货号 | 130-101-549 |
描述 | CD171 (L1CAM) MicroBead Kit was developed for the direct isolation or depletion of CD171 (L1CAM)+ neurons from dissociated mouse brain tissue derived from mice younger than eight days (<P8). |
性能供应商 | Miltenyi |
背景 | CD171 (L1CAM) MicroBeads (L1CAM: L1 cell adhesion molecule) have been developed for the separation of mouse cells based on the expression of the CD171 (L1CAM) antigen. Expression of the cell adhesion molecule CD171 is found on tetanus-toxin positive neurons1, endothelial cells, certain epithelial cells, reticular fibroblasts, and several malignant tumors including colon and breast carcinomas, colon melanoma, tumor cells of neuronal and mesothelial origin, where a role of CD171 in augmenting tumor growth has been demonstrated. CD171 plays a vital role in cell adhesion and signal transduction. It is involved in the development of the nervous system and regulates processes such as neuron–neuron adhesion, myelination, axonal guidance, and neuronal migration. |