Anti-mPDCA-1 MicroBeads, mouse
货号:
130-091-965 基本售价:
询价 规格:
EA
产品信息
概述货号 | 130-091-965 |
描述 | Anti-mPDCA-1 MicroBeads have been developed for the enrichment of mouse plasmacytoid dendritic cells (PDCs) from lymphoid tissues. |
性能供应商 | Miltenyi |
背景 | The mouse plasmacytoid dendritic cell antigen-1 (mPDCA-1) is specifically expressed on mouse PDCs, a subset of CD11c+ dendritic cells detected at low frequency in all lymphoid tissues, peripheral blood, and some non-lymphoid tissues. In mouse spleen, bone marrow, and lymph nodes, mPDCA-1 is exclusively expressed on cells which are CD11clow, CD45R (B220)+,Ly-6Chigh, MHC Class IIlow, CD8alow/-, CD80low/-, CD86-, CD40-, CD11b-, CD90-, CD49b (DX5)-, CD3-, CD19-, i.e. on cells with the phenotype of mouse PDCs. Multi-color fluorescent staining of spleen cells clearly revealed, that all CD11c+ CD45R (B220)+Ly-6C+ PDCs are mPDCA-1+ and that mPDCA-1 expression is restricted to PDCs in non-treated mice. |