iNOS/NOS Type II Pure 2/iNOS 150ug
货号：
610600 基本售价：
8300.0 元 规格：
150ug
产品信息
概述| 货号 | 610600 |
| 描述 | Nitric oxide synthase (NOS), a cell-type specific enzyme, catalyzes the synthesis of nitric oxide (NO). NO is a short-lived radical that transmits cellular signals involved in vasorelaxation, neurotransmission, and cytotoxicity. In macrophages and other cell types, NOS (iNOS or macNOS) activity increases following exposure to cytokines (IFN- γ , TNF- α , and IL-1) and microbial products (lipopolysaccharide (LPS)). iNOS isactivated independently of Ca2+/calmodulin and its level of expression is tightly controlled by several transcription factors, including NF κ B. Data indicates that TGF-ß affects translation of iNOS mRNA and decreases iNOS protein stability. Normally undetectable in brain tissue, iNOS mRNA has been observed in CNS tissues of animals under experimental pathologic conditions. iNOS and nNOS share 51% amino acid homology with the greatest degree of divergence in the calmodulin binding domain. |
| 别名 | NOS Type II |
| 同种亚型 | IgG1 |
| 反应种属 | Mouse (QC Testing) |
| 来源宿主 | Mouse |
| 使用方法 | WB, IF |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse iNOS aa. 772-787 |
| 存放说明 | Store undiluted at -20°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
|
| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
