INTEGRIN ALPHA V BETA 5 A647 ALULA 50UG
货号：
565836 基本售价：
8215.0 元 规格：
50ug
产品信息
概述| 货号 | 565836 |
| 描述 | The ALULA monoclonal antibody specifically binds to Integrin alpha v beta 5 ( αvβ5 ), which is also known as CD51/β5. Integrin αvβ5 is widely expressed by fibroblasts, endothelial cells, and vascular smooth muscle cells. It is involved in activation-dependent cell migration and cell adhesion to t he extracellular matrix. Integrin αvβ5 play s a major role in growth factor-induced angiogenesis in response to VEGF and TGF. The αv Integrins, αvβ5 andαvβ3, αre involved in tumor growth and are being targeted in cancer therapies. The ALULA clone specifically recognizes α v β5 integrin and functionally block s the interactio n between α v β5 and vitronectin. Although raised against mouse αvβ5 , the ALULA antibody crossreacts with human αvβ5. |
| 别名 | Integrin alpha v beta 5; αVβ5; CD51/β5 |
| 同种亚型 | Mouse 129, also known as 129/J or 129/SvJ IgG |
| 反应种属 | Human (QC Testing) Mouse (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse fibroblasts expressing αvβ5 |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated to Alexa Fluor® 647 under optimum conditions, and unreacted Alexa Fluor® 647 was removed.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
