ShcC Pure 23/ShcC 150ug
货号：
610643 基本售价：
7961.0 元 规格：
150ug
产品信息
概述| 货号 | 610643 |
| 描述 | Mammalian ShcA is expressed as three proteins of 46 kDa, 52 kDa, and 66 kDa. Each protein contains a C-terminal SH2 domain, a central glycine/proline rich sequence, and an N-terminal phosphotyrosine-binding domain (PTB). All three Shc proteins become tyrosine phosphorylated by activated growth factor receptors and oncogene tyrosine kinases. Two additional murine genes with Shc homology have been identified and named ShcB and ShcC. The ShcC gene encodes a protein of 475 amino acids and mobility of 55 kDa. Additional immunoreactive proteins have been observed with apparent molecular weights of 69 kDa and 100 kDa. These could be due to extended 5 sequences inthe ShcC gene. In contrast to widely distributed ShcA proteins, expression of ShcC is restricted to the nervous system and spleen. |
| 同种亚型 | IgG1 |
| 反应种属 | Rat (QC Testing) Human, Mouse (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | WB, IF |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse ShcC aa. 239-374 |
| 存放说明 | Store undiluted at -20°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
|
| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
