SHP2/PTP1D Pure 79/PTP1D/SHP2 150ug
货号:
610622 基本售价:
7961.0 元 规格:
150ug
产品信息
概述货号 | 610622 |
描述 | SHP2 (also known as PTP1D, Syp, SHPTP2 and PTP2C) is a member of the cytosolic class of protein-tyrosine phosphatases (PTPs). SHP2 has been reported to contain two SH2 domains where both SH2 domains are N-terminal to the PTP catalytic domain. The expression of SHP2 has been reported to be highest in brain, heart, and kidney. The PTPs are thought to function with other protein-tyrosine kinases to maintain intracellular protein phosphotyrosine homeostasis and cell cycle progression. The presence ofSH2 domains in SHP2 (PTP1D) has prompted speculation that binding to specific phosphorylated tyrosine residues is key to its function. SHP2 (PTP1D) is tyrosine- phosphorylated and activated in response to stimulation with EGF or PDGF. |
别名 | PTP1D, Syp, SHPTP2 and PTP2C |
同种亚型 | IgG1 |
反应种属 | Human (QC Testing) Mouse, Rat, Dog, Chicken, Frog (Tested in Development) |
来源宿主 | Mouse |
使用方法 | WB, IP, IF |
性能供应商 | BD Pharmingen |
免疫原 | Human PTP1D (SHP2) aa. 1-177 |
存放说明 | Store undiluted at -20°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
浓度 | 250 µg/ml |